MILS-16 offers an up to date evaluation of the influence of alkali steel ions on lifestyles. Their bioinorganic chemistry and analytical selection, the cast country constructions of bio-ligand complexes and the houses of alkali steel ions in resolution within the context of every kind of biologically proper ligands are lined, this contains proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na⁺) and potassium (K⁺) are considerable within the Earth's crust, making Na⁺ and K⁺ simply to be had. by contrast, the alkali parts lithium (Li⁺), rubidium, and cesium are infrequent and the radioactive francium happens simply in strains. because the intra- and extracellular, in addition to the compartmental concentrations of Na⁺ and K⁺ fluctuate considerably, homeostasis and energetic shipping of those ions are vital; this consists of transporters/carriers and pore-forming ion channel proteins. structures like Na⁺/K⁺-ATPases, H⁺/K⁺-ATPases or Na⁺/H⁺ antiporters are completely mentioned. The position of K⁺ in photosynthesis and the position of Na⁺ in charging the "battery of lifestyles" are mentioned. additionally, the relationships among alkali steel ions and ailments (e.g., Parkinson or nerve-racking mind harm) are coated and the relevance of Li⁺ salts in drugs (pharmacology and mechanism) is reviewed. This and extra is handled in an authoritative and well timed demeanour within the sixteen stimulating chapters of quantity sixteen, The Alkali steel Ions: Their position for Life, that are written through forty four the world over well-known specialists from 12 countries. The effect of this bright examine quarter is manifested in approximately 3000 references, over 30 tables and greater than a hundred and fifty illustrations (two thirds in color). MILS-16 additionally presents first-class info for teaching.

Astrid Sigel, Helmut Sigel, and Roland okay. O. Sigel have long-standing pursuits in Biological Inorganic Chemistry. Their examine makes a speciality of steel ion interactions with nucleotides and nucleic acids and on comparable issues. They edited formerly forty four volumes within the sequence Metal Ions in organic Systems.